Sentence examples for normal outgrowth from inspiring English sources

The important reduction of the neuritic arbour caused by transfected TIMP-1/GFP compared to GFP alone confirms that TIMP-1 interferes with normal outgrowth of cortical neurons regardless of its locus of synthesis.

However, Shh target genes are expressed throughout the walls of the RP and are required for its normal outgrowth and differentiation [ 4].

Human-in-mouse normal outgrowth tissue sections were stained with an antibody for α-smooth muscle actin (1 1000; Vector Laboratories, Burlingame, CA, USA).

The UNC-6/netrin signal is released from ventral ectoderm [ 23] to repel growth cones expressing both UNC-40 and UNC-5; this interaction is required for normal outgrowth of DA motor neuron commissures to the dorsal nerve cord [ 15].

Simultaneous treatment with both verapamil (10 μM) and Aβ1 42 (5 μM) resulted in a partial protection of normal outgrowth (Fig. 5G, second dark gray histogram), similar to the protective effects of isradipine, although this response was not significantly different from preparations treated with Aβ1 42 alone (P<0.09).

To investigate whether the mutant phenotype results from a failure of the dendritic tree to arborize or whether it is a consequence of atrophy following normal outgrowth, we carried out a time course experiment in organotypic cerebellar slice cultures of Mwk mice compared with their wild-type littermates.

Furthermore, the high rate of abnormal outgrowths associated with Cobra1−/− blastocysts is unlikely due to delayed growth, because longer periods of in vitro culturing (up to 7 days) did not improve the percentage of normal outgrowths from the Cobra1−/− embryos (data not shown).

Sorted breast lobules and sections from human-in-mouse normal outgrowths were stained with antibodies for cytokeratin (CK) 8/18 (1 250, Vector Laboratories) and CK 14 (1 250, Thermo Scientific, Tewksbury, MA, USA).

When miRNA-200c levels were restored in any of these cells, they lost the ability to proliferate in vitro, as demonstrated by a dramatic decline in clonogenicity, and they lost the ability to proliferate in vivo, as demonstrated by an inability to generate tumors or normal outgrowths upon orthotopic implantation in mice.

We have previously shown that actin capping protein beta2 subunit, Capzb2, binds tubulin and, in the presence of tau, affects microtubule polymerization necessary for neurite outgrowth and normal growth cone morphology.

Although it is not yet clear whether MeCP2 is a direct target of CDKL5, Chen et al. (2010) have shown that CDKL5 is required for normal neurite outgrowth, a process that is altered in RTT neurons (Jellinger et al., 1988).