Sentence examples for normal membrane function from inspiring English sources
We conclude that the homeostatic mechanisms that preserve normal membrane function vary: (1) with the nature of the stress that perturbs fluidity, (2) with local conditions within each tissue, and (3) possibly with the thermal tolerance of individual species.
Macrolide antibiotics have also been shown to bind to negatively charged phospholipid bilayers and interfere with normal membrane function [ 55, 56].
Thus, although membrane lipid remodelling in metabolically compensated obese individuals might help to maintain normal membrane function, it might also make the adipose tissue more vulnerable to inflammation.
Sterols facilitate normal membrane function by controlling their fluidity, but they have also been implicated as ligands for nuclear receptors directly affecting transcription and signal transduction pathways [ 51].
This method allows the analysis of the inhibitory effect of drugs within minutes instead of hours, identifying a direct effect on the putative targets before the cells react by modifying their FA composition to sustain normal membrane functions.
At least 48 h is necessary for the cells to recover normal plasma membrane functions.
Prenylation of Ras is required for its normal membrane localisation and function (Rowinsky et al, 1999).
An important component of the HSR is the synthesis of Heat Shock Proteins (HSPs) which protect normal protein and membrane function.
In particular, regarding stored fatty acyl residues in the phospholipids, polyunsaturated fatty acyl residues have been paid special attention in schizophrenia research because they are essential to maintaining normal membrane structure and function as well as to normal brain development [ 3].
Fodrin is important for maintaining the normal membrane structure and supporting cell-surface protein functions.
The function of TRPM4 channel is well documented in maintaining the normal membrane potential of an immune cell and controlling the Ca2+ flux mechanism.
