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MST1/2 signalling further regulates normal lung functionality (Table 1).
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IPF < 50% FVC indicates a pulmonary fibrosis patient with poor lung function; COPD > 80% FEV1 indicates a chronic obstructive pulmonary disease patient with relatively normal lung function.
All had never smoked, and had normal lung function.
All subjects have normal lung functions.
Normal lung function was defined as FVCpred≥70%andFEV1pred≥80%0%.
Controls comprised smokers with normal lung function and non-smokers with normal lung function.
Recovering regular or near-normal lung function.
The lungs become a mass of cysts that supplant normal lung tissue.
Finally, despite normal lung volume, Tgfbi-null lungs displayed diminished elastic recoil and gas exchange efficiency.
Joly-Battaglini, A. et al. Rituximab efficiently depletes B cells in lung tumors and normal lung tissue.
CD73−/− mice had normal lung development in room air compared with wild-type controls.
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