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Alternatively, if Wnt is acting as a permissive factor, this manipulation would not affect the directionality of the instructive cue, resulting in normal guidance of the anteriorly-directed D-type processes.
Flowers of pop2 mutants with low levels of GABA (200 uM) displayed normal guidance, while increases in GABA to 100-fold above that level caused severe defects in guidance in vivo and decreased pollen tube growth in vitro[ 50].
Alternatively, the route of the M1 axon may be physically constrained by surrounding pharyngeal tissues such that the axon sometimes extends properly when normal guidance cues using g1P or the growth cone are compromised.
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A robust high accuracy tracking of the missile normal acceleration guidance command is achieved in presence of considerable model uncertainties created by the interactions between the airflow and the thruster's jets.
Hence, normal axon guidance pathway function may be of importance to develop and maintain nervous system health.
EVE is also essential for normal axonal guidance and innervation of the RP2 motoneuron [19] thus EVE can provide clues as to whether the observed alterations in cell fate lead to faulty axon pathfinding and innervation.
cwn-1 mutants have normal axon guidance of the D-type neurons, as do the remaining two Wnt mutants, cwn-2 and mom-2, and the cwn-1 mutation does not increase the severity of the lin-44 mutant phenotype (Fig. 1G, Fig. S2).
unc-33 encodes a microtubule-binding CRMP protein that is exclusively expressed in neurons and is required for normal axon guidance and elongation (Maniar et al. 2012).
WL Library preparation and Illumina sequencing of the tumor and normal samples, guidance and training of additional staff for library preparation and sequencing.
He says the view in the Bank of Canada is that in normal times policy guidance is not very helpful.
Protein abundances calculated with 3 different algorithms (NSAF, PAF and emPAI) provide a relative quantification under normal condition as guidance.
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