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Ddb1 f/f::Vav1Cre + mice were born at normal frequencies and were indistinguishable from littermates.
The patients had no history of severe or opportunistic infections, normal peripheral T-cell counts and normal frequencies and absolute numbers of CD4 helper and CD8 cytotoxic T cells.
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The former include pure tone (normal frequency and extended high-frequency range), speech and impedance audiometry, auditory brainstem responses, and Distortion Product Otoacoustic Emissions (DPOAEs) testing.
Mutants in seven additional genes formed zygotes at near normal frequency and displayed at most modestly reduced spore formation relative to wild type.
Samples were obtained through breathing at normal frequency and tidal volume until a total expiratory volume of 180 L was achieved.
They were asked to breathe at a normal frequency and tidal volume, wearing a nose clip, for a period of 10 min. If subjects felt saliva in their mouth, they were instructed to swallow it.
These changes, however, did not have long-term effects on sexual habit, which appeared to return to normal frequency and similar to that of conventional chemotherapy by about 12 months from treatment.
Taken together, this dKO spermatocyte phenotype indicates that while physiological DSBs priming recombination events are induced with normal frequency and kinetics, RAD21L and REC8 complexes are evidently involved in cooperative non-redundant pathways leading to axial elements formation followed by the assembly of the synaptonemal complex [ 36].
After DT injection, DKO* mice reconstituted with control B6 bone marrow (B6 → DKO*) had normal frequencies of LCs and Lan+ DDCs, and disease remained constant (Fig 5B D and H).
In the F2 population, FT, PH, RTN, SN, and SW displayed approximately normal frequency distributions and transgressive segregation, and only SSP had a negatively skewed frequency distribution.
A detailed analysis of Ikaros−/− mice that show evidence of ongoing thymopoiesis without bone marrow B cell development revealed normal frequencies of ETPs and absence of classical bone marrow CLPs [3].
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