Since this is a non-interventional study and characterization of sera' reactivity is accepted and expected by the patients as normal diagnostic procedure, no written consent was required according to the local Swiss, French, German and Japanese ethics committees.
At a minimum, though, this sort of analysis could provide an additional source of data for physicians to incorporate into their normal diagnostic procedure.
Since ethical regulations also required methods to be non-invasive when possible, assessment of constipation need to be done without the rectal digital examination, which will therefore provide less information in comparison to the normal diagnostic procedure.
We are aiming to use [F]-FACBC-PET in dose planning for external beam radiation therapy and in normal diagnostic staging procedures, especially in restaging of biochemical relapse.
In most cases this syndrome is the reason why those patients also go through several (and fairly normal) standard diagnostic procedures, and therefore the final diagnosis is likely to be referred to a compensation reward expectation.
A PAP smear was defined as normal if no further diagnostic procedures were suggested and abnormal if the cytologist recommended a follow-up.
Radiation exposure to normal brain tissue during therapeutic and diagnostic procedures is unavoidable and radiation has been shown to affect brain function [ 1- 3].
