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Given that an i.v. immunization schedule based on 500 γ-spz does not lead to sterile protection against normal challenge, a minute proportion of the s.c.-inoculated γ-spz that might have made their way out of the skin to liver would not account for the protective immunity we obtained in our model.
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The new normal challenges the optimism that's been at the root of American success for decades, if not centuries.
"This system has been fully implemented and is experiencing the normal challenges one would expect from a major overhaul of this kind," Ms. Stainback said.
Despite their numbers, immigrant entrepreneurs must navigate a sea of obstacles beyond the normal challenges that all small business owners face.
Think about it: in addition to the normal challenges facing all schools, charter school administrators are forced to become finance wizards, real estate gurus and city building-code specialists.
Many parents, though, do not know what to look for or how to distinguish a true sleep disorder from the normal challenges of putting an infant or child to bed.
In addition to the normal challenges, President Obama and his staff suffered through a number of surprising headaches.
Although simulated obstetric emergencies are frequently reported in the literature, childbirth and the postnatal period involve normal physiologic processes, and therefore a focus on "normal" challenges in immersive perinatal simulations may provide students with vital uniform clinical learning experiences.
The Alabama race is, even above the normal challenges of polling, incredibly difficult to predict.
The moments of grace exist within this regular life, filled with normal challenges and frustrations.
The astronauts, whose task it is to repair a critical cooling system necessary for keeping the outpost fully powered, have an additional concern to the "normal" challenges of a quickly-planned extra-vehicular activity (EVA, or spacewalk).
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