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Thus, GH plays a regulatory role in normal cardiac physiology that is independent of the beta-adrenergic system.
In normal cardiac physiology, action potential durations (APD) shorten to accommodate for increases in heart rate [29] [33].
In normal cardiac physiology, action potential durations (APD) shorten in response to elevated heart rate, which is a necessary accommodation in order to maintain a proper ratio of time spent in electrical systole to time spent in diastole [29] [33].
Despite reduced SERCA2a levels in heart, Atp2a2 heterozygous mice resembled humans in exhibiting normal cardiac physiology.
Further investigation is warranted to determine whether GLUT8 directly influences myocardial glucose utilization or has a separate role in influencing normal cardiac physiology.
The aim of the present review is to discuss the direct and indirect role of AMPK in normal cardiac physiology and in cardiometabolic disease, and therapeutic strategies in modulating APMK activity.
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Engineered 3D cardiac tissue constructs (ECTCs) can replicate complex cardiac physiology under normal and pathological conditions.
Cardiac physiology and telemetry responses were not measured in this study.
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