Sentence examples for normal cardiac development from inspiring English sources

Despite the clear indications for HGF to effectively treat post-ischemic heart failure, the knowledge on the role of the HGF/Met system in normal cardiac development is still limited.

SNIP interacts through the BMP signaling pathway which is essential for normal cardiac development.

Klf13 is highly expressed in adult hearts [18] and is required for normal cardiac development in Xenopus [19].

Similar to cardiac hypertrophy, also normal cardiac development relies on increased cell size, mRNA, and protein synthesis and P-TEFb activity seems to be responsible for these effects.

More recently, it has been noted that this protein might also act as a morphogen, at least in the context of normal cardiac development (Lee et al. 2010).

The microRNAs and microRNA clusters have been implicated in normal cardiac development and also disease, including cardiac hypertrophy, cardiomyopathy, heart failure, and arrhythmias.

Cardiac specific expression of p57Kip2beginning at E9.5 did not appear to be deleterious, as R26loxpTA-p57 k /+ ;Mlc2v-Cre k /+ transgenic mice displayed normal cardiac growth both during development and postnatal life.

In the present study, we speculate that expression of genes controlling normal cardiac ganglia development is altered by maternal diabetes, thereby leading to disruption of the differentiation of the cardiac ganglia.

Whether hemodynamic forces and shear stresses resulting from blood flow are required for normal early cardiac development is controversial.

This review discusses components of the Mediator complex and the contribution of the Mediator complex to normal and pathological cardiac development and function.

A loss-of-function homozygous mutation in the FTO gene shows a defect in normal brain and cardiac development [ 325], in line with previous observations in animal studies.