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Bladder carcinoma and autologous normal bladder tissue specimens were procured from 36 patients undergoing transurethral resection.
Four samples of normal bladder tissue were used as comparison.
Normal bladder tissue (from cystectomies for nonmalignant indications) was obtained from the BWH with IRB approval.
In normal bladder tissue, the majority of PHB was localized to the nucleus.
Normal bladder tissue biopsies were obtained from individuals with no history of bladder tumours.
This difference may be because our array used a panel of cell lines as reference rather than normal bladder tissue.
Similar(17)
Bladder cancer tissues and paired adjacent normal bladder tissues were collected.
Wnt5a and Wnt7b mRNAs were both expressed in normal bladder tissues and bladder tumours.
The expression levels of 12 proteins were altered between bladder cancers and normal bladder tissues.
As shown in Figure 1A, EIF5A2 protein levels were elevated in BC tissues compared with adjacent normal bladder tissues.
H3K27me3 expression could be evaluated informatively in 113/126 of UCB tissues and 61/72 of normal bladder tissues.
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