Sentence examples for nor mouse from inspiring English sources

An alternative possibility is that the difference in non-class II MHC genes in NOR and NOD mice may contribute to the functional difference between NOD and NOR mouse Treg.

NOD mouse Treg, specific for GAD peptides, were IL-10-dependent and cell contact-independent, while NOR mouse GAD-specific Treg were IFN-γ and NO-dependent as well as cell-contact dependent [16], [17], [18], [23].

In order to better understand the function of autoantigen-specific Treg from NOR mice, as well as their role in T1D development, we have isolated NOR mouse CD4+ T cells specific for an immunodominant p286 (a.a. p286 300) peptide of a major autoantigen, glutamic acid decarboxylase (GAD), involved in T1D.

It binds above-background levels of antibodies from only about a third of the NOD and NOR mouse serum samples and cross-reacts with antibodies in 10% of the control Swiss mouse samples (Table 1).

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NOR mice are a diabetes-resistant recombinant congenic strain of NOD mice [24], [25].

NOR mice are a class II MHC I-Ag7-bearing recombinant congenic strain of NOD mice.

NOR mice are diabetes resistant but contain greater than 90% of the NOD genome, including the unique IAg7 MHCII [39].

We report here a novel population of Foxp3-negative GAD p286-specific NR286 Treg isolated from NOR mice.

While both strains express the same disease-associated I-Ag7 molecules, NOR mice are resistant to T1D.