Sentence examples for nonresponsive in from inspiring English sources

It is a disease that is nonresponsive in patients who have never achieved a minor response with any therapy.

Proposals addressing perturbation of biological processes in the absence of extension to human disease will be considered nonresponsive in the context of this solicitation.

Whereas tumour-infiltrating lymphocytes were nonresponsive in the proliferation assays, lymphocytes from sentinel nodes proliferated dose dependently and secreted interferon- γ upon stimulation with tumour homogenate.

In this comparison, 90% of the mutant forms that were responsive in male Fabry patient lymphoblasts were also responsive in HEK-293 cells, whereas 92% of those that were nonresponsive in male Fabry patient lymphoblasts were also not responsive in HEK-293 cells.

However, due to the irregular shape and the small size of FR, the core encroached slightly on proximal representations in case 472, and both proximal representations and nonresponsive area in case 1884.

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The application of adalimumab can also be hypothesized beside nonresponsive uveitis in panuveitis and pediatric uveitis [ 47, 48].

In developing novel QoL instruments, we hope to gain further insight into the interests and lived experiences of behaviorally nonresponsive patients in order to positively impact their care.

This system utilizes a mutant strain of Drosophila in which the 2 native receptors of the ab3A neuron have been deleted, this creates a nonresponsive Δab3A in which other receptors can be expressed and functionally tested.

The predictive potential of this data is predicated on the fact that within 2 to 4 weeks after the start of therapy, gene expression in responsive patients, as measured by DFA, became more like that in healthy controls, while gene expression in nonresponsive patients became less like that in healthy controls.

In contrast, many residues that are mutated in nonresponsive forms of α-Gal A were located within, or in close proximity to, the active site (Fig. 4B).