Sentence examples for nonlinear disposition from inspiring English sources

In contrast, the closed conditions are easier to apply in a numerical analysis of nonlinear disposition of solutes in organs.

The kinetics of disposition is described as a nonlinear disposition function of the lipophilicity, acidity, reactivity, and 3D structure of chemicals.

The present model provides important insights into the nitrite hemoglobin interactions and the nonlinear disposition of nitrite, nitrate and methemoglobin in humans.

As the ultimate outcome of the SBSP modeling, the kinetics of disposition is expressed as a nonlinear disposition function of properties, with adjustable coefficients containing the biological and chemical attributes, which do not vary under given experimental conditions.

Target-mediated drug disposition (TMDD) is a nonlinear PK phenomenon, where drug target binding (complexation with receptors, enzymes, or transporters) and subsequent events (dissociation and drug-target complex degradation) result in dose-dependent changes in PK (Mager & Jusko, 2001).

The published TCZ phase III PK/PD model consisted of a population PK model with two disposition compartments and two parallel elimination pathways (linear and nonlinear) describing the serum concentration time course of TCZ and a PK/PD model describing the relationship between the serum concentrations of TCZ and CRP via a direct sigmoidal Emax formalism.

By carrying out a nonlinear inversion, we obtained optimum values for all eight parameters that determine the dimension and the disposition of the open crack (Table 2), with the volume change of the crack estimated at 1.56 × 105 m3.

Nonlinear CL has been reported for other monoclonal antibodies and is thought to reflect target-mediated drug disposition.

It's nonlinear.

These are nonlinear kids with nonlinear lives.

Disposition: Claim thrown out.