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Nonetheless, as requested by Reviewer #2, we now provide new data (new Figure 1 figure supplement 2C) that directly address this issue by showing that CIP treatment of WT Fps1 collapses the isoforms to a migration pattern identical to Fps13A.
Nonetheless, as requested by Reviewer #2, we have added a sentence to the Discussion pointing out that it is possible that the response to hyperosmotic shock might be mediated by some influence on the Slm1 and Slm2 proteins, and we cite the Berchtold et al. reference in this context (although the Berchtold paper was already cited in our original manuscript).
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Greensleeves, as requested.
I did as requested.
West did as requested.
We edited as requested.
We corrected this as requested.
Interpreters were used as requested or needed.
We have modified the Discussion as requested.
The text has been revised as requested.
Then it was administered as requested.
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