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I do think that the cover plays a lesser, non-essential role on an e-book, and I take this fact as further evidence that the physical book will survive.
This difference in activity between RNF125 and RNF114 was the starting point of our study and led, through the generation of chimeras and stop mutants, to the identification of an essential role of the C2HC ZnF in the activity of RNF125, and a contributing, non-essential role for a linker region.
One possibility for this non-essential role of Drosophila dGIPC is redundancy.
In Saccharomyces cerevisiae, depletion of eIF5A reduces global protein synthesis by about 30%, suggesting that it has an accessory, non-essential, role in protein synthesis [12].
Current evidence supports a direct interaction of frataxin with components of the mitochondrial ISC synthesis machinery, but a non-essential role in the process [27].
This is consistent with the observation that a plasmid-cured strain of A. tumefaciens was less able to suppress infection by TMV [17], and suggests that plasmid-borne genes play a minor, but non-essential role in SA suppression.
Similar(33)
"All staff with non-essential roles are currently being asked to work from home," a spokesman said.
The second is that the assembly process is highly efficient in vivo, and most factors play important, but non-essential roles, which makes it impossible to isolate factor-specific intermediates for functional assays.
Therefore, large amount of repeats in proteins is less likely to be regarded as 'junk proteins' [ 99], which merely have non-essential roles.
Of this set of potential key factors, 16 were known to play either essential or non-essential roles in the regulation of adult definitive erythropoiesis and were used as a reference dataset for training the machine learning algorithm.
Given the importance of the Hsp70 family in essential cellular functions and also that Hsp70 is a potential therapeutic target for a variety of human diseases, it is important to understand Hsp70s essential and non-essential roles within the cell and to characterize the functional difference between members of this chaperone family.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com