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The challenge in CAD for urinary stones lies in the similarity in shape and intensity of stones with non-stone structures and how to efficiently deal with large high-resolution CT volumes.
By the time the myriad research-driven "best-in-class" package, the carryover architecture, the manufacturing wants, the non-stone chip rocker placement, the carryover sunroof module, and on and on, are loaded in, and the whole thing is given to Design with the words, "Here, wrap this for us," the ship sailing toward that dreaded destination, "Lackluster," has already left the dock.
But one can deny that A3 is true without accepting that there is a sharp transition from stones to non-stones in such series, that is, without accepting that there is some specific object in the series which definitely is a stone and whose successor definitely is not a stone.
However, 14% of the patients had non-stone-related findings that required immediate or deferred treatment.
In general, stone formers tend to excrete urine that is more supersaturated than that of non-stone formers.
Furthermore, in a report based on the Third National Health and Nutrition Examination Survey (NHANES III), obese stone formers had a modest decrease in estimated glomerular filtration rate (eGFR) compared with non-stone formers [ 15].
For typical urine from non-stone formers, the critical pH is well above the physiological pH so that normally the fluid is not expected to be unstable with respect to calcium phosphate precipitation or to contain calcium phosphate nanoclusters.
Moreover, a retrospective case-control study based on data from the Rochester Epidemiology Project found stone formers to have a 51%to68%68 % increased risk for a sustained elevation in serum creatinine (SCr) and for a clinical diagnosis of CKD compared with non-stone formers [ 3].
As such we would attain 85% power with a minimum of 80 ureteral stones and a minimum of 256 non-stones.
de la Torre, I. & Mora, R. A technological analysis of non-flaked stone tools in Olduvai Beds I & II.
It sounds like it means that Google made money selling non-Rosetta Stone ads that would appear when people searched for "Rosetta Stone".
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com