With a recent report showing that the localization of a bacterial protein is determined by a geometric factor [23], [24], namely, membrane curvature, the importance of assessing potential contribution of other non-specific properties to protein localization in the cell is additionally emphasized.
Other TEDs did not form a fibrinogen adduct under the conditions of the assay, indicating this activity is not a generic, non-specific property of TEDs.
High rate of proliferation, active migration, and invasiveness into non-neoplastic tissues are specific properties of neoplastic transformation.
The isolation of a nystatin-like polyene from a leaf-cutting ant-associated Pseudonocardia species in this work agrees with the report by Sen et al. [ 11] that some Pseudonocardia bacteria associated with attine ants have non-specific antibiotic properties that inhibit a range of fungi and are not targeted specifically at Escovopsis [ 11].
Previous development of general anesthetic drugs has always been empirical, or based on non-specific physicochemical properties, such as hydrophobicity.
73 74 75 76 77 Warfarin has relatively non-specific anticoagulant properties, inhibiting the production of factors II, VII, IX, and X.
LPC has non-specific detergent properties at high concentrations, preventing use of a concentration that generated maximum TRPC5 activity.
Some authors have proposed that the mPTP is a component of the Ca2+ efflux system due to the non-specific channel properties that were observed during its opening [17,34].
SRL172 is a suspension of heat-killed Mycobacterium vaccae, a fast growing avirulent mycobacterium, that may have non-specific immunomodulating properties, e.g. it may promote Th1 and down regulate Th2 cytokine production (Grange et al, 1995).
Besides probe specific properties like the (non- radiative decay rate of the inon- radiativeonic transitions also experimental parameters like sample absorption, collection andecayection efficiency of the given setup deteratee the number of dethetable photons.
The wide clinical anti-cancer effect in combination with specific properties such as non-cell cycle specific and direct cytotoxic effect has also rendered MMC an attractive drug for use by topical administration, utilized in the treatment of as diverse malignancies as bladder cancer and certain tumors of the eye [ 4, 5].
