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This is a non-specific method to deplete thiol concentration versus the specific method using BSO.
However, the writhing test is a non-specific method for evaluation of pain [ 37].
Writhing test is a non-specific method for evaluation of pain [ 35].
In addition, hypothetical choices were examined in terms of a non-specific "method of family planning" and not in terms of actual methods such as oral contraceptive pills, etc.
As such, while ABC transporters are a major mechanism of chemoresistance, there is evidence that specific and non-specific methods of overcoming ABC transporter pump activity may be useful for improving chemotherapy against CSCs.
In contrast to the relatively non-specific methods mentioned above, numerous techniques have been developed for targeting and isolating single rare cancer cells from large populations of histologically diverse cells such as peripheral blood (Fig. 2).
These methods are applied to investigate how health outcome data relate spatially by identifying: (i) the presence of any clusters, in which case global (general, non-specific) methods are used; and, (ii) the location of clusters in space, for which local (focused, specific) methods are used (Lawson 2001; Lawson et al. 2016).
In comparison to modern immunohistological techniques, it is unknown how sensitive these non-specific methods are in detecting difference in changes in beta cell mass.
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