Interestingly, with ARID1A, this process is at least partially independent of its ARID domain, which binds DNA in a non-specific manner only (Dallas et al., 2000).
A problem regarding AV-45 binding is that it is suggested to bind in a non-specific manner to the white matter [12].
While the presence of such a radiometabolite is a complication, it does not necessarily preclude the quantification of radiotracer retentions, if the radiometabolite distributes uniformly in the brain in a non-specific manner.
The initial sensory awareness of external objects which does not grasp any special features of them, nonetheless illuminates them in a non-specific manner as mere things by such expressions as 'this' or 'that' (Bhartṛhari; 123 and 124).
Trichophyton tonsurans is the foremost fungal pathogen of minority children in the U.S. Despite overwhelming infection rates, it does not appear that this fungus infects children in a non-specific manner.
The guide-target RNA duplex formation triggers HEPN1 domain to move toward HEPN2 domain, activating the HEPN catalytic site of Cas13a protein, which subsequently cleaves both single-stranded target and collateral RNAs in a non-specific manner.
This comprises cells and other mechanisms that defend the host from infection in a non-specific manner.
The capsule impeded cell-association while the LPS saccharides increased cell-association in a non-specific manner.
As an evolutionarily conserved and ancient defense strategy, the innate immune system responds instantaneously to invading pathogens in a non-specific manner.
As shown in Figure 5 (red curve), up to 200 ng/cm2 of AC were able to bind to the cysteamine-coated surface in a non-specific manner.
Nevertheless, our data provide strong evidence that once activated by the TCR or during polyclonal expansion, T regs may exert their suppression in a completely non-specific manner.
