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A ratio of titration rate was calculated for each NMS patient and "rapid escalators" and "non rapid escalators" were compared.
The cumulative dose for the "non rapid dose escalators was also markedly higher (6102.5 mg for"non rapid escalators" vs. 512.4 mg for the "rapid escalators" vs. 893.8 mg for clozapine titrators in the first 15 days and 5817.2 mg for"non rapid escalators" vs. 4219.9 mg for the "rapid escalators" vs. 2600 mg for clozapine titrators during days 16 30) (Table 6).
Four patients (30.8%) received a lower total dose- of those receiving a lower cumulative dose; two were rapid escalators and two non rapid escalators.
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