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For non operable, non metastatic disease, preferred endpoints were PFS (81%), QoL (63%) and response (56%).
An unexpected endpoint was metastatic PFS in non operable oesophageal (31%) and pancreatic (44%) cancers.
For non operable tumours, PFS (88%), QoL (50%) and metastatic PFS (44%) were the best rated endpoints.
Of 10 patients who initially had stage IV, 7 patients underwent gastrectomy and 6 patients, including 3 non operable patients, received palliative chemotherapy.
In case of non operable, non metastatic disease, PFS (69%), response (63%), DFS (50%) and metastatic PFS (31%) were ranked number 1, 2 and 3, respectively.
DFS, in the neoadjuvant settings or early stages, and PFS, in the non operable or metastatic settings, were ranked first, with a frequency of more than 69% in 20 out of 22 settings.
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