Similar(60)
Local control rate which includes central and parametrium relapses was considered as an event, and censored at the time of death, non-local relapse, or last follow-up.
Nevertheless, there was no statistically significant difference in response rates or local relapse survival rates between patients receiving or non-receiving cetuximab.
However, 12 patients had another recurrence: five were local (four of which were successfully salvaged — 2 with further local resections and two with subsequent limb amputation), four developed lung metastases, two developed local relapse with synchronous lung metastases, and one patient relapsed with non-pulmonary metastases.
Current data indicate that the triple negative group is more prone to visceral metastases, local relapse and cerebral metastases rather than bone metastases as compared to women with non-triple negative tumors [ 13- 15].
Very recently the TARGIT-A data [ 7] reported a non-inferior efficacy of tumor bed irradiation with single dose intraoperative radiation (Intrabeam system, Carl Zeiss Oberkochen) compared to WBRT regarding local relapse.
Local relapse.
As expected, the local relapse of tumor was appreciated 1 year after the R1 surgery.
Local relapse of residual cancer cells was macroscopically appreciated as an inevitable consequence of R1 surgery.
In literature, a great variability of local relapse (LR) detection rate is reported.
However, local relapse also depends on the biological characteristics and interstitial spreading of cancer cell [4].
Local relapse after R1 surgery was controlled by chemoradiation for long term in the current case.
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