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We note that, although the nominal coverage of the evaporated In is more than several monolayers (ML), post annealing removes surplus In layers and establishes the ( 7 × 3 )-In surface.
Mixed-effects model was most efficient and attained nominal coverage of 95%and90%0% power in almost all scenarios.
ECs, for each scenario combination, evaluating the 95% nominal coverage of the TI approach, are shown in Table 3.
The nominal coverage of the 95% point-wise bootstrap confidence intervals is similar for both sample sizes.
Patient - level models A - C guaranteed nominal coverage of confidence intervals at different ICC values, whereas the other models were likely to produce lower coverage under certain conditions.
Failure to account for this co-variance may result in inaccurate confidence intervals, that is, the nominal coverage of e.g. 95% will not be accomplished.
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Wald-type CIs maintained a nominal coverage rate of 90%, except for the intermediate Tmax case which just missed the nominal rate (89%, data not shown).
In order to investigate the accuracies of the procedures in terms of (i) controlling the pre-assigned type-I error level under the null hypothesis, (ii) maintaining the nominal coverage probability of the corresponding simultaneous confidence intervals, and (iii) their powers to detect certain alternatives, extensive simulation studies were conducted.
We developed permutation tests to assess the significance of the covariates association with the outcome in RF, BRT and LASSO; their results with UFMLR were comparable to that of the Wald test in terms of nominal coverage (see Additional file 1).
In comparison with complete data, Tobit regression and the multiple imputation approaches are the only methods that achieve nominal coverage over a broad range of simulation parameters, although the multiple imputation begins to degrade when more than about 50% of the measurements are below DLs.
While the usual likelihood-based CIs covered the true values of the parameters with the nominal coverage probabilities, the subsampling CIs were conservative, that is, their coverage probabilities were larger than the nominal coverage probabilities.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com