Mitochondrial DNA (mtDNA) is usually overlooked in whole-genome ChIP-seq analyses, since identification of enriched peaks is more difficult here due to a much higher noise, consequence of the high and variable number of mtDNA copies in the cell.
The inability to hear tone and nuance, the frustration and pain of the riot of white noise, had consequences that Coleman had not envisaged.
"Kerry has been making noises about consequences for violations of the ceasefire, but I don't think the Americans have much to offer, or anything that will change things in a significant way," one opposition adviser said.
While increasingly precise experimental measurement methods are being developed, cell-cell heterogeneity in tissues and stochastic noise, the consequence of the small copy number of some intracellular components, are intrinsic sources of uncertainty and require ad hoc methods of analysis.
But even animals that can change their calls may not be able to adapt quickly enough to the loudening world, because noise exposure has consequences beyond impeded communication.
Traffic noise has large consequences on the appreciation of the living quality close to roads and leads to speech interference, sleep disturbances, and general annoyance.
As a consequence, noise develops in the numerical solution and these models can even become numerically unstable at high resolution.
Real data will contain other sources of error the simplest of which being shot noise, an inevitable consequence of quantum mechanics which is more prominent in low-current situations (the signal to noise ratio scales with (sqrt {I}), where I is the beam current).
The difference from mesophilic-hyperthermophilic genome-matched controls is also significant, suggesting adaptive forces beyond random noise or mere consequence of genome reduction.
In recent years rigorous studies on the health consequences of noise have indicated that noise elevates heart rate, blood pressure, vasoconstriction and stress hormone levels, and increases risk for heart attacks.
