These sub-networks containing a set of proteins (nodes) with a distinct set of connections (edges) can represent a functional unit in a pathway or in a biological process.
We ran many simulations with distinct node populations to evaluate how often the network formation process results in oscillations in practice.
As a first step, we propose the construction of networks with nodes of distinct types, representing different ontological categories of entities, and edges of distinct types, representing different types of causal interactions or other biologically significant relations (e.g., homology, collocation the tendency to appear in the same place) occurring between these entities.
31 Similar to the elucidation of the role of cytotoxic CD8+ T cells in T1D pathogenicity, the creation of a panel of highly diabetogenic CD4+ T cell clones from pancreatic lymph nodes of diabetic NOD mice with distinct autoantigenic specificities and, in turn, TCR transgenic models has allowed for detailed examination of the role of CD4+ T cells in disease pathogenesis.
In the 104th Congress, no two politicians voted in the same way on every bill, so we do not have distinct nodes with 0 distance between them.
For any two successive RSS messages that originated from the same identity, the receiver will need to determine whether the messages that are received are from the same legitimate node or from two distinct nodes with the same identity.
(ii) The number of times the motif appears in the real network with distinct sets of nodes is at least U = 2. (iii) The number of appearances in the real network is significantly larger than in the randomised networks: Nobserved - Nestimated > 0.1 Nestimated.
In approximately 25% of the patients, the synovial tissue contains cellular infiltrates that have formed organized structures resembling structures normally observed in lymph nodes, comprising follicular dendritic cells (FDCs), with distinct T-cell and B-cell areas, therefore referred to as ectopic lymphoid structures.
Major lymph nodes, especially the axillary lymph nodes, were small, ranging from 0.5-1 cm in diameter with distinct cortico-medullary junctions.
