Sentence examples for nodes of interaction from inspiring English sources
Interestingly, one of the central nodes of interaction for the top upregulated genes in the HIS was TGF-β (Additional File 5), a pathway that was also found statistically enriched in the HIS by both IPA and Gene Set Enrichment Analysis (GSEA) toward curated canonic pathway gene sets (Additional File 6).
We conducted pathway analysis of miRNAs linked to cardiac autophagy, using the Ingenuity Pathway Analysis (IPA) software (Ingenuity Systems, Qiagen, Redwood City, CA, USA), and discovered two main nodes of interaction, that is p53 and STAT3 (signal transducer and activator of transcription 3).
Analyzing at a finer level the two regions of the map, it became clear that there are five central nodes of interactions, enlarged in Figure 4b.
These results suggest that mammalian cryptochromes, Cry1 and Cry2, represent a node of interaction between circadian clocks and the cellular response to genotoxic stress.
Scoring the nodes of the interaction network solely with flux data resulted in molecular interaction paths dominated by components of sphingolipid metabolism and protein-protein interactions between them (Additional file 2: Figure S1; FunCat enrichments in Additional file 1).
Detailed information about genes integrated in nodes of protein protein interaction network.
Even for proteins, the most studied nodes of biological interaction and function, there is much to discover about how form relates to function.
Based on the gene-network analysis, four genes were identified that appear at central nodes of an interaction map generated by using the caspase-3/7 screening dataset, PDPK1, IKBKB, SRC, and BCL2L1 (BCL-XL).
(e.g., number of nodes, number of interactions).
Specifically, the networks differ in their numbers of nodes, numbers of interactions, average directed path lengths, and average clustering coefficients.
These routines check for name, type of nodes, type of interactions, and logical or syntactical inconsistencies in accession codes.
