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The top-5 nodes obtained using the proposed algorithm are 33, 0, 32, 2, and 1.
The network constructed in this way has 38% of nodes isolated, i.e., with node degree equal to zero, and when we simulated the SEIR model only 63% of the infected nodes coincided with the infected nodes obtained using the same model on our contact network.
Furthermore, the robustness of the nodes obtained using each method was estimated by performing 1,000 bootstrap replicates [ 62].
Comparison of the nodes obtained using only the topological features (Table 2) with those nodes obtained using both topological and biological features (Table 3 revealed that eight nodes were common to both: p53, c-Jun, STAT3, c-Myc, RARA, STAT1, ESR1, and STAT3.
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Step 11: Alternatively, previously calculated weights associated with features describing the nearest subtopic or sub-story or goal or topic node obtained using method described in this work can indicate a change of policy where previously suboptimal action can become optimal and vice versa.
An overview of the current distribution of nodes was obtained using Google Earth (Fig. 6).
Initial locations and movements of the nodes are obtained using the random waypoint (RWP) model of NS-2.
The approximate ages for internal nodes were obtained using the divergence of basidiomycetes and ascomycetes (Taylor and Berbee 2006; Lucking et al. 2009), conservatively set at 500 Ma, and the whole-genome duplication event within the Saccharomyces clade (Wolfe and Shields 1997), set at 100 Ma.
(d) TF module ranking For the module rankings, each node within the module was annotated with the Node Strength obtained using equations (9) and (10).
Succinctly, the underlying features of the proposed method are as follows: a sequence of predicted optimal control values over a finite horizon, for an optimally chosen input node, is obtained using Model Predictive Control ideas; the entire resulting sequence is sent to the chosen input node; a smart actuator is used to store the predictions received and apply them accordingly.
The PDR of a node is obtained using the method MeasurePDR.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com