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Importantly, SialylLewisx is thought to be associated with metastatic ability of tumor cells, and has the potential to be used as a marker for pathological tumor extensiveness, e.g., nodal extension or distant metastasis [ 24].
The outcomes and patterns of failure in patients with and without extracapsular nodal extension (ECE) were compared and analyzed with respect to the radiation target volume design.
mRNAs for ~ 50 ion and gap junction channels, Ca2+-handling proteins and markers were measured in the atrial muscle (AM), a transitional area (TA), inferior nodal extension (INE), compact node (CN), penetrating bundle (PB) and ventricular muscle (VM).
The fluorescent primary tumor was removed en bloc with the seminal vesicles and a meticulous fluorescence-assisted exploration was conducted to establish the presence of periaortic nodal extension, as well as adrenal, liver, and lung metastasis.
Twelve patients (30%) had extra-capsular nodal extension.
This suggests that the left nodal extension is functionally important.
Similar(40)
The first is that there are 2 nodal extensions.
These nodal extensions have been implicated in slow pathway conduction.
Right and left nodal extensions have also been demonstrated in rabbits and guinea pigs.
There are also reports of right and left nodal extensions in humans.
For radiotherapy treatment planning (RTP), sensitivity and specificity of contrast-enhanced computerized tomography (CT), the standard method for tumor volume delineation, are insufficient for defining primary tumor boundaries and nodal extensions [ 4- 11], emphasizing the need for novel tools.
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