For transcripts with <1.2-fold change in baseline expression with No-AS AdVs, subsequent analysis employed an interpretation with AdV-infected conditions, using statistical testing [one-way ANOVA with SNK (Student-Newman-Keuls) post-test and Benjamini and Hochberg multiple testing correction] and filtering on the basis of >1.5-fold difference between AS-Atf3 and No-AS infected cells.
However, we find in our subsequent analysis no significant influence of the duration of the workout-process on the recovery rate.
Although the LC scales the absolute value of the K i data, it is important to note that the choice of LC has no bearing on the subsequent analysis of glucose correlation, between-animal coefficient of variation [COV], or test-retest reproducibility.
Hence, numerous fixed effects were estimated in the subsequent analysis, although no real difference existed between them.
We interpreted this as evidence that the questions were equally difficult, and therefore made no distinction between questions in subsequent analysis.
Subsequent analysis revealed no clinically important abnormalities in laboratory safety test results, ECG measurements or vital signs assessments relating to these AEs.
An initial finding of increased risk of bladder cancer after 2 years' exposure with pioglitazone (HR 1.4 [1.03 2.0]; P = 0.03) was reported in the first article; however, there was no signal reported in the subsequent analysis either after 5 (1.17 [0.79–1.49]; P = NS) or 8 (1.07 [0.87–1.30]; P = NS) years.
However, our subsequent analysis revealed no mutation in the die-1 locus of ot108 mutant animals and, moreover, the ot108 mutant phenotype could not be rescued with a genomic piece of DNA that rescues a canonical die-1 allele (data not shown).
Therefore, no further frictional effect is included in subsequent analysis.
Given that the primary efficacy endpoint was not significantly different no subsequent statistical analysis was conducted.
