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"no significant issues" is correct and can be used in written English.
The phrase can be used when discussing a situation where there may be minor issues, but nothing major or life-altering. For example: After completing the project review, there were no significant issues identified.
Exact(10)
According to a Ford spokeswoman, Jennifer Moore, the company has experienced no significant issues with batteries and has replaced only "a very small number," under warranty.
In 2008, however, there were no significant issues when Serbia and Croatia played in the Fed Cup, the women's team competition, in the Croatian capital, Zagreb.
These results are consistent with other electronic diary usability studies conducted with older adults which found no significant issues with ease of use of electronic formats [25, 26].
The north west was facing sporadic snow showers, especially around Glencoe, but there were no significant issues with the main trunk routes.
Citigroup analyst Mark Mahaney said in a research note that "We believe that a Yahoo sale to Microsoft — at a price higher than the initial $31 bid is the most likely outcome" and that the limited combined market share of the combined companies would raise no significant issues with Government regulators.
Because of our measured approach to the transition, there were no significant issues to correct once MeetMe went live, but we still wanted to do something to get members feeling great about the new brand, so we launched a Youtube channel, MeetMeVideos.
Similar(49)
We've not seen any significant issues of [spending] volume.
No other significant issues were identified.
Farage told the former chairman of the Equality and Human Rights Commission Trevor Phillips that legislation barring discriminating on grounds of nationality or race was no longer required because race is no longer a significant issue in modern-day Britain.
The Ukip leader said laws barring discrimination on grounds of nationality or race were not required because race is no longer a significant issue in modern Britain.
But I'm also worried by Clegg's analysis that economics is no longer a significant issue in politics, a strange position to take in light of the Northern Rock collapse and in a party with so many excellent economists at its disposal.
More suggestions(15)
no significant causes
no major issues
no significant difficulty
no significant safety
no significant item
no significant material
no significant violence
no significant correlations
no significant gains
no significant problems
no significant changes
no significant amounts
no unresolved issues
no significant results
no such issues
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com