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The mean changes in secondary endpoint variables were very small, and there was no significant intervention effect on any of these endpoints (at significance level 5%).
No significant intervention effect was found for sedentary time or motility.
Results: There were no significant intervention effects for physical activity or secondary outcomes at any assessment time.
For the safety outcomes, no significant intervention effects were observed.
Three other recent pilot trials, however, found no significant intervention effects on cognitive outcomes.
There were no significant intervention effects based on objectively measured physical activity.
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One high-quality RCT reported no significant intervention-control group differences in client cognitive status during any study periods [ 30].
The remaining one low-quality quasi-experimental study revealed no significant intervention-control group difference in client depression after six months [ 41].
For example, one review revealed that most included studies found no significant intervention-control group differences in client satisfaction, physical functioning, mortality, or quality of life [ 54].
In contrast, one moderate-quality RCT demonstrated no significant intervention-control group differences at any study periods [ 38], while another low-quality RCT found that the control group had significantly higher satisfaction with care during one-year study period [ 45].
One moderate-quality RCT reported no significant intervention-control group differences in the number of ADL or IADL disabilities during six-month and 12-month follow-up periods respectively [ 38].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com