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Therefore, magnetic microvesicles with glucose oxidase may be designed as a novel theranostic approach for restoring glucose homeostasis and spatiotemporally control NO release for maintaining good overall diabetic health.
The stable biosensor response provided by the sustained NO-releasing sensor membranes highlights the utility of NO release for continuous glucose monitoring.
This could be particularly relevant in patients with COPD who may require local NO release for antimicrobial host defence or preservation of ventilation/perfusion matching within the lung [ 23].
To further investigate the dependency upon NO release for the increased apoptosis observed with the NO-donor containing compounds we co-incubated neutrophils with PTIO, a NO scavenger (Fig. 4c).
Based on Figure 3A, P seems to saturate at 1, meaning that there is little or no release for the next 200 ms. This is one reason the SNR calculation may be misleading.
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