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The one intervention that has been shown to be helpful in preventing CIN is saline hydration, but no one regimen has demonstrated clear superiority[ 13 ].
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This was the first study to show the superiority of any one regimen over PE for the treatment of ED SCLC, and IP has become one of the standard regimens for ED SCLC in Japan.
Spitzer-Index, Instrumental Activities of Daily Living Scale (IADL), EORTC QLQ-C30,-LC13 Booton R et al. (2006) [13] Clinical trial, III NSCLC III/IV Docetaxel/Carboplatin vs. Mitomycin C/Cisplatin/Vinblastine vs. Ifosfamide/Cisplatin secondary No superiority of one regimen.
There is no clear indication that one regimen is superior to the other in terms of 'quality of life', generally the initially more severe reaction in the CHART group being offset by the longer duration of symptoms in the conventionally treated group.
The drug is counted only once when a patient was taking the same medication on more than one regimen (e.g. long- and short-acting morphine).
However, there is conflicting data on the superiority of one regimen over the other.
There were no significant differences for those allocated to one regimen or the other (Table 3).
However, there are few papers prospectively comparing regimens, and while some have favoured one regimen over another there is no clear consensus.
All are accepted regimens so there is no clinical need to be 97.5% certain that one regimen is better than the other.
In total, 13 patients previously underwent one regimen of chemotherapy, and 31 patients underwent no less than two regimens.
If more than one regimen was used, we assigned the spectrum based on the first.
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