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In the worm, only one N-terminal variant was detectable containing a secretion signal but no NtA domain [11].
Notably, secreted PopB and PopD proteins were undetectable in the absence of NTA (no NTA, Fig. 7).
The class III phenotype of deregulated secretion of ExoU was recapitulated for these derivatives (no NTA, Fig. 5D).
In uninduced conditions, the expression of these proteins within bacteria was low or undetectable (bac, no NTA, Fig. 5B), suggesting the dominant expression and secretion of parental PcrV.
In a calcium-rich environment, expression and secretion of ExoU were tightly controlled by PcrV, L63A, and D133A and the regulatory system was perturbed only when pcrV was deleted (no NTA, Fig. 7C).
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(TA – tranexamic acid, NTA – no tranexamic acid) A higher proportion of patients in the no tranexamic acid (NTA) group received a transfusion and returned to theatre for investigation of excessive blood loss.
Chemical oxidation with concomitant biological NO consumption was modeled by assuming complete NO removal and subsequent lack of Fe(II -NTA-NO complex formatII -NTA-NO
Ninety-five ChinEFL EFlearnersrs were randomly assigned to an argumentative writing task under three conditions: metacognitive thinking aloud (MTA), nonmetacognitive thinking aloud (NMTA), and no thinking aloud (NTA), after they completed a similar baseline writing task.
Using a 5' RACE approach in C. elegans only one isoform was found, containing a signal sequence but no laminin-binding NtA domain.
Evans et al [ 22] combined a retrospective case review with a prospective observational study investigating the effects of tension applied (TA) (n = 103) from splinting in the first three weeks following Dupuytren's surgery versus no tension applied (NTA) (n = 165).
The study incorporated nine no-take areas (NTAs) across four countries (two in Seychelles, four in Kenya, two in Tanzania and the long-term de-facto protection of reefs of the Chagos archipelago [30]).
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