Sentence examples for no major mutations from inspiring English sources

Moreover, the Albanian data set included only therapy-naïve subjects and no major mutations associated with drug resistance were identified in such a cohort [15].

No major mutations associated with integrase dug resistance have been found in the pretreatment samples, however the polymorphic variation was common.

No major mutation for resistance to non-NRTIs was found.

Regarding PI mutations, no major resistance mutations were observed in our study.

26, 57 Although no major resistance mutations against dolutegravir have been identified thus far, the accumulation of multiple mutations is required to result in a fold-change > 10, confirming that next-generation integrase inhibitors possess a higher genetic barrier than raltegravir and elvitegravir.

The majority of patients with VF on second line ART have no major PI mutations, indicating that VF in most cases is not the result of antiretroviral resistance [ 10- 12].

Scientists are reporting a significant milestone for cancer research after charting 21 major mutations behind the vast majority of tumours.

Thus, for the run under investigation, there is no bias in the neutrality of major mutations that could explain the downward trend in genome size.

More recently, however, no vertical transmission of NNRTI and PI major mutations has been observed, even when representing the predominant maternal variant [5].

Despite the extensive sequencing analysis over the last decade, no major point mutations have been identified in CLL or ALL.

Viral loads were significantly higher among patients with major mutations, compared with patients minor/no mutations, although no differences in the CD4 counts were found.