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This means it requires a light touch, but no major modification of my mousing style was required to use it.
No major modification was found for the sensitivity and the negative predictive value.
The present study demonstrated that the induction of LTB4 production in response to NSAIDs or NS-398 in OA osteoblasts involved no major modification of 5-LO expression, in contrast to the situation observed in OA chondrocytes [ 56].
In our institution, since the validation of definitive CRT and in accordance with the international guidelines, there was no major modification of oesophageal carcinoma therapeutic strategy during the period of the study [ 6, 7].
Furthermore, chronic alteration in the HPA axis activity is unlikely as adrenal weights were also identical in the two genotypes (Table 2), suggesting that there was no major modification in the long-term corticosterone secretion as a result of increased level of forebrain 5-HT2C receptors.
Similar(54)
However, the heating curves became more reproducible and no major modifications to the heater circuit and/or re-tuning of the controller were made at that time.
It doesn't take a rock scientist to figure out that the Cinema Displays are due for a refresh in the near future since no major modifications have been made since their debut in 2004.
The selected ternary eutectic solder alloy SnAg3.8Cu0.7 requires higher processing temperatures which could restrict the use of certain board and component types, but other than that no major modifications seem necessary.
Until a recent revision of the toxic substance law, there had been no major modifications of American environmental law since 1990.
Little to no major modifications were made to the two active Colorados in the opening months of the U.S.'s entry into the war; all of the battleships in the Pacific Fleet had a constant order to be ready to sail within 48 hours in case of a Japanese attempt to invade Hawaii or the West Coast and could not be spared for any major yard work.
No major modifications were recommended.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com