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Here, no enhanced effect on histone H3K4- or H3K9 methylation was found by treating the cells with TSA in combination with T (Figure 4C).
The study incorporates temozolomide treatment as well, although no enhanced effect is seen when combining the two drugs.
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Interestingly, both of these antibiotics showed an enhanced effect with specific bacteria, compared to control or AgNPs alone.
Hydrogen also has an enhanced effect of chloride ions on a decrease in breakdown potential.
Tan also noted that the background vocals were pitch shifted to increase tonal quality and create an enhanced effect during the chorus.
Higher doses and longer treatment led to an enhanced effect: 14 day treatment with 15 mg/kg q.d.
The combination would be expected to produce an enhanced effect.
Therefore, the administration of NOS inhibitors could cause an enhanced effect of SSRIs in antidepressant therapy.
On the other hand, El Kaffas et al. [ 17] did not observe an enhanced effect on apoptosis.
Melphalan is an alkylating agent with an enhanced effect in hypoxia [ 52] and in HIF-1α inhibited cells [ 53].
This would explain why we do not observe an enhanced effect in the combined BMEC BMS assay model.
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