Sentence examples for no efficacious from inspiring English sources

Currently, animal models for SUCLA2 deficiency are lacking, the underlying disease mechanisms are poorly understood and no efficacious treatments are available.

Presently, no efficacious psychosocial interventions exist for teenage drivers with ADHD.

Currently there are no efficacious preventive measures or therapeutic tools to control PEDV in the US.

Pancreatic ductal adenocarcinoma (PDAC) continues to be a lethal disease with no efficacious treatment modalities.

Therefore, no efficacious therapy to treat CAMR is presently available to prevent the progression of CAMR to kidney allograft failure.

The mechanisms of phosgene-induced pulmonary injury are not fully identified, and currently there is no efficacious countermeasure.

For example, E2 supplementation before ischemia was no longer efficacious in protecting the brain against permanent MCAO in young rats if they were OVX for 10 weeks before insult [21].

However, a survey showed that most pastoralists reported that vaccines were no longer efficacious.

In Nigeria, traditional remedies against malaria have always been employed, though with unproven efficacy, while chemoprophylaxis with weekly pyrimethamine and chloroquine which were widely utilised in several African countries are no longer efficacious because of emergence of resistance [ 5- 7].

These studies have shown that, in the context of mGlu2 and mGlu4 heterodimerization, mGlu4 PAMs that bind to a specific binding site are no longer efficacious when mGlu2 is present; other PAMs retain or exhibit enhanced potentiation in the presence of mGlu2.

Antimonial drugs are no longer efficacious in Asia due to drug resistance (2), and the best currently available treatments for anthroponotic VL are miltefosine and liposomal amphotericin B. Undoubtedly, both drugs are vastly superior to previous therapies, but they also have their limitations.