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DETA-NO, a long-acting NO donor, and SperNO, a rapid releasing NO donor both inhibited TNF-α-stimulated MAdCAM-1 expression in a concentration dependent manner.
Treatments (100 ng/ml) were: Vehicle (control), l-NAME (NOS inhibitor), l-NMMA (NOS inhibitor), DETA (control), DETA-NONOate (NO donor), sodium nitroprusside (NO donor), or ET-1.
Commercial silicone tubing was impregnated with the NO donor SNAP using the previously described swelling method27.
We have recently developed tert-dodecane S-nitrosothiol (tDodSNO) as a photoactivated nitric oxide (NO) donor.
The effects of NO donor on caffeine-induced coronary vasoconstriction were examined by isometric tension recordings.
So, molsidomine was used as a NO donor in this study.
Similar(6)
The phenolic quinolyl hydrazone ligand behaves as monobasic bidentate (NO- donor with O- bridging).
The selected NO-donor moieties were nitrooxy and furoxan.
Phenylsulfonyfuroxan nitric oxide (NO -donor pheNO -donor designed, synthesized and evaluated.
When incubated in hepatic homogenate, VA694 acted as a slow NO-donor.
The compounds were designed through a symbiotic approach using selected phenols and phenylsulfonylfuroxan NO-donor.
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