Your English writing platform
Discover LudwigSuggestions(2)
Exact(1)
Although the general EMA biosimilar guidelines state that RCTs for efficacy are usually required, the EMA insulin-specific guideline states that there is no anticipated need for specific efficacy RCTs because end points used in such studies, usually level of hemoglobin A1c (Hbare), are not considered sensitive enough for the purpose of showing biosimilarity of two insulins.
Similar(57)
Conclusion: Some patients are transfused because of institutional bias of an anticipated need rather than for true surgical bleeding.
We explore in which extent the notion of a reconfigurable vehicle, presented as an innovation, is an anticipated need given the current patterns of vehicle occupancy.
In 1989, a Consensus Conference on Artificial Airways in Patients Receiving Mechanical Ventilation [ 21] recommended translaryngeal intubation for an anticipated need of up to 10days and a tracheostomy if an artificial airway for more than 21days is anticipated.
Ongoing system support would also require strengthening with an anticipated need to hire a full-time customer services support firm that is familiar with mobile phone technologies and computer systems, but not necessarily a programming expert.
To be included in the study, patients had to fulfil the following criteria: 18 years of age or older; critically ill with an anticipated need for mechanical ventilation of at least 24 hours; not moribund; not suffering from pneumonia at admission; no fractures in the facial skeleton or the base of the skull; no oral ulcers; not immune deficient; not a carrier of HIV or viral hepatitis.
Exclusion criteria included patients with acute coronary syndrome, a known history of vasospasm or asthma, any patients currently experiencing bronchospasm, patients with active bleeding with an anticipated need for transfusion of >4 units of packed red blood cells, hemoglobin <7 g/dL, or any other condition that would contraindicate drawing serial blood samples.
Subjects who required treatment with ocular or systemic corticosteroids or any other topical or systemic treatment for OAG or OHT, or had an anticipated need to initiate or modify medication that was known to affect IOP (eg, β-adrenergic antagonists, α-adrenergic agonists, calcium channel blockers, ACE inhibitors and angiotensin II receptor blockers) were also excluded.
The 2001 National Kidney Foundation KDOQI guidelines stated that patient "with chronic kidney disease should be referred for surgery to attempt construction of a primary AV fistula when their creatinine clearance is < 25 mL/min, their serum creatinine level is >4 mg/dL, or within 1 year of an anticipated need for HD… (Opinion)" [ 8].
The depletion of many forests, especially in the tropics, makes uncertain the provision of an adequate wood supply to satisfy the anticipated need.
A DEA spokeswoman, Barbara Carreno, explained that in previous years, the DEA added a 25% "buffer" to the anticipated need for opioid medications to create quotas that would allow additional production in the event of a drug shortage.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com