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If no evidence of transport or biochemical transformations of the metabolite in M. tb was found, no additional reactions or transporters were added.
If no evidence of transport or biochemical transformations of the metabolite in F. tularensis was found, no additional reactions or transporters were added.
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We extended the network originally proposed by Hu and coworkers [22] by introducing additional reactions involving NO, as well as additional compounds such as the NO-related species FeLnNO (L denotes ligands that do not contain heme), NO2, and cytochrome c oxidase (CcOx).
This second model version resulted in the addition of about 150 additional reactions.
On the basis of the observed decrease in reactivity of PM collected along an upwind downwind trajectory in the Los Angeles air basin, it appears that, at least in that air basin at that time, photochemical aging occurred rapidly, on a time-scale of a few hours during daytime, and that little or no additional heterogeneous reactions would occur for additional atmospheric transport times.
Calculations were conducted with a detailed chemical mechanism based on GRI-Mech-2.11 with additional reactions characterizing thermal DeNOx chemistry and modified HCCO + NO reaction rates.
Ninety-six of these 280 additional reactions consisted of newly added enzymatic activities, for which no apparent genes were present in the annotated R. sphaeroides genome.
Additional reactions will be posted by me in the comments below.
This report was updated with additional reactions from Facebook and Collins.
This report was updated to include Collins' response statement, and with additional reactions from Grimes and Vote Leave.
*Update, 1 October, 4 00 p.m.: This article has been updated with additional reactions and quotes.
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