Exact(1)
Except for a large hydropic placenta, no additional anomaly was noted at autopsy.
Similar(59)
The missing incisors do not cause a major change in appearance because the gaps between the teeth close during development, and the team found no additional anomalies among the skeletons, nor any evidence that the individuals with MLIA were treated or buried differently.
This study found that, on average, children with a cleft and no additional anomalies had three admissions and spent around 2 weeks in hospital before their second birthday.
The deprivation differences presented here could not be explained by either variations in the acquisition of additional cytogenetic anomalies or TKI resistance, both of which were rare in this population: 7 (3.4%) of the 209 Ph+ patients with no additional abnormalities at diagnosis (table 1) acquired an additional anomaly during the follow-up, and all were in deprivation categories 1 3.
In BL, the most frequent additional anomaly is the duplication of 1q [31] [31].
Based on in silico analysis and control data, the authors classified two missense and one nonsense (p.R286X) variants as pathogenic mutations; no inheritance pattern analysis was performed, and no additional systemic anomalies were documented for any of these cases (Lubbe et al. 2011).
There was no significant temporal trend among children with additional anomalies.
21.0% were excluded because of additional anomalies or syndromes.
Of these children, 2410 (22.1%) had additional anomalies (table 1).
35.2% of children without additional anomalies had at least one emergency admission, whereas the corresponding figure was 67.3% with additional anomalies.
Children without additional anomalies spent on average 6.3 days in hospitals for cleft-related care and children with additional anomalies 8.5 days (table 2).
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