Sentence examples for nitrogen mustard from inspiring English sources
noun
Any of a series of compounds, analagous to mustard gas with sulfur replaced by nitrogen, that have been used in the treatment of cancer
In cancer chemotherapy, the first effective drug was nitrogen mustard.
The toxicity of nitrogen mustard on lymphoid tissue caused researchers to study the effect of nitrogen mustard on lymphomas in mice.
Direct-acting carcinogens include organic chemicals such as nitrogen mustard, benzoyl chloride, and many metals.
Modern blister agents include sulfur mustard, nitrogen mustard, phosgene oxime, phenyldichlorarsine, and lewisite.
In the early 1940s nitrogen mustard (mechlorethamine) was discovered to be effective in the treatment of human lymphomas.
Then, in 1969, Dr. Karnofsky, a 55-year-old nonsmoker, died of lung cancer, caused perhaps by his work with nitrogen mustard in World War II.
In 1946, the government gave Dr. Goodman's team permission to publish the first paper on the use of nitrogen mustard in cancer treatment.
The first time a patient was treated with cyclophosphamide, the active part of nitrogen mustard, the tumour shrank – something not even thought possible at the time.
While investigating chemical warfare agents in 1942, Dr. Goodman's team noted that the blood of soldiers exposed to nitrogen mustard had abnormally low levels of white cells.
Following the principle that "the dose makes the poison", scientists wondered if a low dose of nitrogen mustard could be used to treat cancer.
A series of novel nitrogen mustard-evodiamine hybrids were synthesized and evaluated for their antitproliferative properties.
