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This nitrite may feed into the nitrite respiration pathway, thereby giving C. concisus a means to respire through the amino acid L-glutamate.
Activation of aerobic respiration and nitrite respiration will accelerate NADH to be reoxidized to NAD+.
Induction of nasDE and narGHI controlled by FNR showed that nitrite respiration is activated by low oxygen supply.
After that, nitrite respiration may proceeds in two different ways [ 44].
Most of these features relate to the nitrate and nitrite respiration.
The duplicated two-component system allows for the fine tuning of the nitrate and nitrite respiration system to a dynamic ratio of two alternative substrates.
Similar(50)
It is not surprising, given that in these bacteria the nitrate- and nitrite-respiration system is strongly reduced, and only nitrate, but not nitrite, is used as an electron acceptor [ 24].
In contrast, C. concisus contains NrfC and NrfD which have been linked to both nitrite and sulfite respiration [ 33, 34].
Instead, nitrite produced upon nitrate respiration is mostly exported outside the cell, likely through predicted nitrite extrusion proteins including NarK3 and NarU [26].
Moreover, the Black sample had a lower concentration of free nitrate than the Red sample, presumably because nitrate is being used as an electron acceptor during respiration (although nitrite was below the level of detection in both samples; Table 3).
Analogous to the short-term test on nitrite accumulation, the short-term respiration test provides information on the microbial activity at the sampling time.
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