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Thus, reproductive failure with age may be due, at least in part, to deterioration of somatic microenvironments (niches) that support stem cell function.
Studies of ATF4 and its mediators in cells derived from long-lived and short-lived species could also produce insights into the possible role of the ATF4 system in evolutionary adaptation to niches that support slower aging and extended lifespan.
The cell-rich, three dimensional structure of EBs increases intercellular contact, stimulating the creation of diverse cell signalling niches that support cell differentiation to a multitude of lineages.
The body contains numerous different ecological niches that support abundant and diverse populations of microorganisms.
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Because neurons produced insulin (Fig 1), we were interested in the niches that supported neuronal differentiation.
The Saanich Inlet fjord system has many discrete habitats: the summer thermocline in Saanich Inlet and an additional halocline from glacial waters mixing at the surface creates ecological boundaries, partitioning species into ecological niches that may support genetically stratified populations of dinoflagellates by sexual and/or environmental selection.
The ENM of C. gattii performed in this study identifies, however, that the Vancouver Lower Mainland has optimal ecological niches that can support the establishment of C. gattii in the local environment.
They describe how different elements of an ecology - tools, specific methods, even humans who occupy specific roles - become established as niches that provide specific functions in support of human activity.
Niches are microenvironments where CSCs reside, containing cell-cell, cell-extracellular matrix, and soluble factors that support the growth, progression, and metastasis of CSCs [ 113].
Some online businesses created niches that did not exist before.
There are stereo speakers stuck in the niches that used to hold the old floor beams.
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