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This suggests that some cercozoan clusters may represent geographycally or ecologically niche-restricted taxa. 2 of our environmental sequences strongly affiliated with the genus Telonema which, to date, comprises only two species described as phagotrophic free-living biflagellated organisms of 6 8 µm in length [44].
In comparison to S. uberis and S. zooepidemicus, S. pyogenes is highly niche-restricted, therefore the spectrum of substrates and stimuli it experiences is narrower.
Host-adapted symbionts (intracellular or niche-restricted) generally have smaller genomes than the free-living bacteria from which they were derived (Moran 2002; Klasson and Andersson 2004).
Exciting progress in multiple studies of specific epigenetic features of human and mouse stem cells has provided insights into the unique properties of pluripotent and niche-restricted stem cells, and outlined the importance of the molecular mechanisms that control these epigenetic events.
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Niche restricted or organ specific infection may afford specific effector functions.
Shigella are a subset of E. coli, which have become niche restricted to the human intestinal tract where they are highly pathogenic, and display extreme monomorphism across a large population set, with little to no recombination.
This can explain the high AT content of obligate endosymbionts or intracellular parasites which are adapted to a restricted niche, undergo restricted gene exchange, and possibly mutate at a high rate due to the loss of DNA repair genes [43].
However it may appear sometimes as a narrow and restricted niche topic when compared to other exploration production disciplines.
This dual life must be evolutionarily challenging and represents a very different and perhaps more restricted niche compared to that of Y. pseudotuberculosis.
Comparisons of complete genome sequences from strains of these two species support the idea of a more restricted niche for Y. pestis, as up to 13% of the Y. pseudotuberculosis genes are no longer active in Y. pestis [7].
This could indicate that MAP-C has evolved more recently or over a long time within a restricted niche.
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