Sentence examples for niche regulation from inspiring English sources

Furthermore, these cells may play an important role in adult stem cell niche regulation and in neurodegeneration.

Identification of niche-modulated genes relied on sustained change in expression following loss of niche regulation.

In addition to Notch signaling, the canonical Wnt/ β-catenin signaling pathway has been reported to play a key role in cardiac stem-cell niche regulation.

Further analysis of the data from a niche-regulation perspective reasoned classification of the niche-modulated genes into four functional categories: Both RGS1 and CD69 regulate leukocyte retention in niche.

Although the coordinated expression of several genes by several different cell types is required to define a functional stem cell niche, the regulation of this coordinated expression is not well understood.

RGS1 attenuates migration and retains cells in niche by regulation of G-protein signaling and reduction of B-cell response to chemokines such as CXCL12.

Assessment of dissimilarities between cell origins (BM versus PL) disclosed two hundred differentially expressed genes enrolled in microenvironment processes related to the cellular niche, as regulation of bone formation and blood vessel morphogenesis for the case of BM-MSCs.

The American companies already here, such as Airbnb, operate in a rare niche between regulations, Feinberg said.

Furthermore, RTE are excluded from the niche-based regulation of peripheral T cell numbers [ 48] and are preferentially selected for survival in the periphery over existing resident T cells [ 47].

In this study, we show that autocrine Wnt2/4 signaling maintains the differentiation niche by regulating ISC proliferation and survival via redox regulation.

Hence, our study establishes a new paradigm for studying stem cell niche and its regulation because in most other systems, stem cell niches are derived from lineages distinct from the stem cells they support.