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Future implementation of NICE Innovation Scorecards to track compliance with NICE TA and other NICE compliance initiatives may further help to reinforce and track the implementation of NICE guidance.
Referring to NICE guidance during 2011, NICE compliance for all units was 65% (range 50-100%), as depicted in Figure 1.
NICE recommendations are diagnosis specific so it would not be possible to assess the impact of NICE compliance without this information.
This regional survey not only provides us with important regional data on NICE compliance regarding switching of biologic drug therapy in RA, but it also informs us of the wide variance in prescribing practice of these drugs.
Overall NICE compliance for all units was 65% (range 50 to 100%), with anti-TNFα to anti-TNFα switches for inefficacy making up the majority of non-compliant switches.
Figures 3 and 4 compare these factors against NICE compliance for individual units.There is a negative correlation between the number of patients on a biologic drug and the percentage of patients having six-monthly DAS-28 assessments in each rheumatology centre.
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The main analysis of the importance of compliance with NICE guidance focused on individuals who had been ascribed an ICD-10 diagnosis by their service, as NICE guidelines are diagnosis specific.
Following the implementation of the booklet, compliance with NICE guidance (see Table 36) improved from 0%to100%0%to100%
However the analysis did not consider whether compliance with NICE guidance impacted on patient outcome.
Logistic regression analyses (see Table 3) confirmed that compliance with NICE guidance was associated with higher recovery rates.
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