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Bennette CS, Trinidad SB, Fullerton SM, et al. Return of incidental findings in genomic medicine: measuring what patients value development of an instrument to measure preferences for information from next-generation testing (IMPRINT).
If a probe card consists of an array of actuator-integrated microprobes, it could be applied to next-generation testing, for instance, a new wafer-level test/burn-in.
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This next-generation test cell provides experimental data under uniform shear, which would enable better validation of mathematical models for UF processes.
Bio-X affiliate Howard Chang is the co-creator of "ATAC-seq" (Assay for Transposase-Accessible Chromatin with high throughput sequencing), a next-generation test for scanning DNA to assess which of its genes are activated.
Other tests that are being considered as "next generation" tests are Smarter Balanced and ACT's Aspire.
Our next generation test, the SNaPshot NGS assay, fully sequences 1000 cancer genes.
Ellingford, J. M. et al. Assessment of the incorporation of CNV surveillance into gene panel next-generation sequencing testing for inherited retinal diseases.
Thus, through our alternative proficiency testing approach, we identified the bioinformatic detection of insertions/deletions as an area of particular concern for clinical laboratories performing next-generation sequencing testing.
Such information may be of value to other health systems seeking to provide next-generation sequencing testing to their patient populations.
Thus, a suggested model for next-generation carrier testing in LMICs is premarital, on a population-by-population basis, tailored to recessive diseases with an incidence greater than, for example, 1 10,000.
Beyond characterizing an "average" response to chemicals, next-generation toxicity testing may improve understanding of population variability, identify vulnerable subpopulations, and refine uncertainty factors used in risk assessment (Zeise et al. 2013).
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