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Next, we interrogated the SDEG to identify the target genes of the STAT1 mechanistic network.
Next, we interrogated the state of the 5hmC mark in other cell types.
Next, we interrogated whether the increased osteoclast burden and osteopenia in Sf mice is due to skewed myelopoeisis secondary to hypercytokinemia.
Next we interrogated these physiomimetic cultures for localisation of FGFR1 and FGF2 in specific cellular compartments (within both cancer and stromal cells), upon PD173074 treatment.
58, 59 Next, we interrogated the regulation by tumor suppressors sub-model, which describes the cell cycle exit characteristic of senescence regulated by the E2F/Rb axis and CDK inhibitors.
Consistent with our previous study, we found that DCIS lesions with high activin A expression exhibited reduced telomere signal (P = 0.03) and higher levels of γH2AX (P = 0.01) and COX-2 (P = 0.01) when compared with lesions with low activin A. Next, we interrogated whether activin A expression levels in a DCIS lesion could reflect the characteristics of adjacent stromal cells in vivo.
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As a next step, we interrogated the entire genome (exonic, intronic and non-exonic regions) for the presence of RNAs that change during different stages of inflammation irrespective of the presence of annotation.
We next interrogated an expanded version of the connectivity-map database (version 2), which includes 7056 genomic profiles representing 6100 individual treatment instances with 1309 bioactive small molecules.
To address whether the GPNMB/OA-associated angiogenic phenotype was specific to the 66cl4 mouse mammary tumor model, we next interrogated the association between GPNMB/OA expression and vascular density in human breast cancer cells and primary tumors.
We next interrogated each species' tRNA phylogeny using DendroPy (Sukumaran and Holder, 2010).
DOI: http://dx.doi.org/10.7554/eLife.04106.032 We next interrogated the impact of this set of antisense transcripts.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com